Detalhe da pesquisa
1.
Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell
; 161(3): 501-512, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25865481
2.
Deubiquitinase-targeting chimeras for targeted protein stabilization.
Nat Chem Biol
; 18(4): 412-421, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35210618
3.
Discovery of Potent Pyrazoline-Based Covalent SARS-CoV-2 Main Protease Inhibitors.
Chembiochem
; 24(11): e202300116, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37069799
4.
An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4.
J Am Chem Soc
; 144(50): 22890-22901, 2022 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36484997
5.
Structure-guided enzymology of the lipid A acyltransferase LpxM reveals a dual activity mechanism.
Proc Natl Acad Sci U S A
; 113(41): E6064-E6071, 2016 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27681620
6.
Molecular characterization and verification of azido-3,8-dideoxy-d-manno-oct-2-ulosonic acid incorporation into bacterial lipopolysaccharide.
J Biol Chem
; 292(48): 19840-19848, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29018092
7.
A Förster Resonance Energy Transfer (FRET)-based System Provides Insight into the Ordered Assembly of Yeast Septin Hetero-octamers.
J Biol Chem
; 290(47): 28388-28401, 2015 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26416886
8.
Rapid analysis of protein expression and solubility with the SpyTag-SpyCatcher system.
Protein Expr Purif
; 117: 44-51, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26405011
9.
Contributions of Hyperactive Mutations in Mpro from SARS-CoV-2 to Drug Resistance.
ACS Infect Dis
; 10(4): 1174-1184, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38472113
10.
Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells.
ACS Chem Biol
; 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38739449
11.
Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB.
Cell Chem Biol
; 30(4): 394-402.e9, 2023 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36898369
12.
Targeted Protein Degradation through E2 Recruitment.
ACS Chem Biol
; 18(4): 897-904, 2023 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36940189
13.
Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses.
Viruses
; 15(3)2023 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36992489
14.
Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon.
Sci Rep
; 13(1): 22088, 2023 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38086859
15.
Ophiobolin A Covalently Targets Complex IV Leading to Mitochondrial Metabolic Collapse in Cancer Cells.
bioRxiv
; 2023 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36945520
16.
Systematic Analyses of the Resistance Potential of Drugs Targeting SARS-CoV-2 Main Protease.
ACS Infect Dis
; 9(7): 1372-1386, 2023 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37390404
17.
Rational Chemical Design of Molecular Glue Degraders.
ACS Cent Sci
; 9(5): 915-926, 2023 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37252349
18.
Correction to "Rational Chemical Design of Molecular Glue Degraders".
ACS Cent Sci
; 9(8): 1702, 2023 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37637749
19.
Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms.
Elife
; 112022 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35723575
20.
Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance.
Nat Commun
; 13(1): 3556, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35729165